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I.Cloze
A single night of taking the drug Ecstasy can cause serious brain damage and hasten the ___1___ of Parkinson's disease, scientists say. Just two to three Ecstasy tablets-a quantity that thousands of clubbers take during raves-can permanently __2____ brain cells that affect movement and ___3___, according to American research that ___4___ the drug to Parkinson's for the first time.
A study by a team at Johns Hopkins University in Baltimore, Maryland, ___5___ monkeys and baboons found that both species of primate __6____ irreversible damage to key cells __7___ dopamine neurons, which are lost in Parkinson's, after receiving three low doses of Ecstasy at three-hour ___8___.
The study is particularly significant because baboons are one of the best animal models for the human ___9___. George Ricaurte, who led the research, said that widespread ___10___ of the drug may already be ___11___ victims of such neurological damage. "The most troubling ____12__ is that young adults using Ecstasy may be ___13___ their risk for developing Parkinsonism as they get older."
Alan Leshner, a former director of the US National Institute on Drug Abuse, said: "This study emphasizes the multi-faceted damage that Ecstasy can do ___14___ users. We've long known that repeated use damages serotonin brain cells. This study shows that even very __15____ use can have long-lasting effects __16___ many different brain systems. It sends an important message to young people: don't ___17___with your own brain."
Janet Betts, the Essex mother whose daughter Leah died after a single Ecstasy tablet in 1995, said: "This comes as no ___18___. People can't see the effects at first, and they're in permanent denial, saying it's not going to happen to them. But we'll see the ___19___ later, just as we have __20____ smoking.
1. [A]outset [B] onset [C]outcome [D]opening
2. [A] destroy [B]demolish [C]ruin [D]wreck
3. [A]intuition [B]understanding [C] reasoning [D]judgment
4. [A]connect [B] links [C]combine [D]unite
5. [A] involving [B]taken [C]involved [D]engrossing
6. [A]made [B]did [C] suffered [D]escaped
7. [A]marked [B]titled [C]naming [D] called
8. [A]time [B]process [C]intermission [D] intervals
9. [A]body [B]heart [C] brain [D]head
10. [A]disuse [B]ill-use [C]misuse [D] abuse
11. [A]requiring [B] claiming [C]doing [D]enduring
12. [A]suggestion [B] implication [C]insinuation [D]intimation
13. [A]enlarging [B]extending [C] increasing [D]expanding
14. [A] to [B]with [C]as [D]for
15. [A]irregular [B]sparse [C] occasional [D]insufficient
16. [A]to [B] on [C]with [D]in
17. [A]do [B]make [C]use [D] experiment
18. [A]amazement [B]astoundment [C]astonishment [D] surprise
19. [A] symptoms [B]signs [C]tokens [D]marks
20. [A]to [B] with [C]as [D]in